This position will provide leadership and direction for the pipeline of an assigned clinical development program. The successful candidate will be responsible for developing and implementing the overall clinical strategy. They will emphasize early clinical development of the asset and be credible within the clinical function, bringing a high level of leadership and accountability. The ideal candidate be a highly innovative, collaborative, scientifically-grounded and accomplished Clinical Development physician with a flexible, hands-on and team-oriented style. The Clinical Development Lead will be be a critical partner to counterparts in Research, Early Development, Regulatory, Clinical Operations, Safety and other expertise areas. He/she will be the AVROBIO program Development spokesperson at external meetings, including regulatory interactions and scientific meetings.