Sr. Clinical Scientist

Our culture is entrepreneurial, inclusive and caring. We're passionate about our work. And we embrace a pioneering spirit. Join us as we strive to develop innovative therapies with the power to give people with genetic diseases freedom for life.

Job Summary

The Sr. Clinical Scientist will collaborate with Clinical (MD) Leads, Clinical Operations, Regulatory, Research and other functions within AVROBIO. The. Clinical Scientist will have a substantial role in protocol development, study execution, review and interpretation of scientific and clinical data and communication with the scientific and medical communities.

Cambridge
Research and Development
Key Responsibilities

• Perform ongoing review and analysis of study data for ongoing clinical trials

• Provide support as needed for scientific issues that may arise during study execution

• Provide strategic and planning support for publication of data (manuscripts, posters, etc.)

• Identify and review literature that addresses specific topics of interest relevant to AVROBIO candidates

• Perform literature searches and critically review and summarize the relevant scientific, drug development and medical literature

• Support document development, such as the investigator brochure, clinical protocols, statistical analysis plans, clinical study reports, competitive assessments, etc.

• Provide scientific/medical supportive materials to in-house staff and external consultants in the indications being studied

• Systematically survey public domain for relevant information from competition, summarize clinical trial designs and data for similar drug products, review and summarize Summary Basis of Approval documents for competitive compounds

• Contribute to the organization, preparation, and execution of investigator and advisory board meetings in collaboration with the project team and external vendors

• Support preparation of scientific material for conference presentations or publications

• Collaborate with cross-functional groups for assigned studies

• Perform other duties as assigned related to clinical programs

Minimum Requirements/ Qualifications

• Advanced, doctoral level degree preferred. PhD, MD, MSc/MPH, PharmD, with 8+ years of experience within a pharmaceutical company environment required

• Gene therapy, Hematology/oncology disease experience preferred

• Excellent management, communication and organizational skills required with demonstrated success in leading projects and interacting with cross functional teams

• Passionate commitment, detail-oriented and a strong team player

• Ability to work independently and reliably deliver objectives of high quality in a timely manner

• Experience in all stages of drug development

• Global clinical research experience

About AVROBIO

AVROBIO, Inc., a leader in lentiviral-based gene therapies, is a clinical-stage company developing disruptive therapies that have the potential to transform patients’ lives with a single dose. The Company is focused on the development of its gene therapy candidate, AVR‑RD‑01, in Fabry disease, as well as additional gene therapy programs in other lysosomal storage disorders including Gaucher disease, Cystinosis and Pompe disease. AVROBIO’s lentiviral platform has broad potential for other rare and non-rare genetic diseases. AVROBIO is headquartered in Cambridge, MA and has offices in Toronto, ON.

AVROBIO, Inc is an EEO employer